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Article

MicroRNA 876-5p modulates EV-A71 replication through downregulation of host antiviral factors

5 Feb 2020

Abstract excerpt

BACKGROUND: Human enterovirus 71 (EV-A71) is a non-enveloped virus that has a single stranded positive sense RNA genome. In a previous study, we showed that miR-876-5p upregulation was observed in the serum of patients with severe EV-A71 infection. Micro-876-5p (miR-876-5p) is a circulating miRNA that can be identified to modulate EV-A71 infections through both in vitro and in vivo studies. However, the...

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PMID: 32024541
DOI: 10.1186/s12985-020-1284-8

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