Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Host MicroRNA miR-197 Plays a Negative Regulatory Role in the Enterovirus 71 Infectious Cycle by Targeting the RAN Protein

19 Nov 2015

Abstract excerpt

UNLABELLED: Enterovirus 71 (EV71), a member of Picornaviridae, is associated with severe central nervous system complications. In this study, we identified a cellular microRNA (miRNA), miR-197, whose expression was downregulated by viral infection in a time-dependent manner. In miR-197 mimic-transfected cells, EV71 replication was inhibited, whereas the internal ribosome entry site (IRES) activity was decreased...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to MicroRNA in disease regulation
Share to RNA Research and Splicing
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26581983
DOI: 10.1128/jvi.02143-15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Host MicroRNA miR-197 Plays a Negative Regulatory Role in the Enterovirus 71 Infectious Cycle by Targeting the RAN ProteinPMID 26581983Read ↗

HuR and Ago2 Bind the Internal Ribosome Entry Site of Enterovirus 71 and Promote Virus Translation and ReplicationSemantic proximity Read ↗

Heterogeneous nuclear ribonuclear protein K interacts with the enterovirus 71 5′ untranslated region and participates in virus replicationSemantic proximity Read ↗

Identification of microRNAs Involved in the Host Response to Enterovirus 71 Infection by a Deep Sequencing ApproachSemantic proximity Read ↗

Differential expression of miRNAs in enterovirus 71-infected cellsSemantic proximity Read ↗

Human MicroRNA hsa-miR-296-5p Suppresses Enterovirus 71 Replication by Targeting the Viral GenomeSemantic proximity Read ↗

Enterovirus-Induced miR-141 Contributes to Shutoff of Host Protein Translation by Targeting the Translation Initiation Factor eIF4ESemantic proximity Read ↗

Enterovirus 71 antagonizes the inhibition of the host intrinsic antiviral factor A3GSemantic proximity Read ↗

Far upstream element binding protein 1 binds the internal ribosomal entry site of enterovirus 71 and enhances viral translation and viral growthSemantic proximity Read ↗

MicroRNA-23b Inhibits Enterovirus 71 Replication through Downregulation of EV71 VPl ProteinSemantic proximity Read ↗

MicroRNA 876-5p modulates EV-A71 replication through downregulation of host antiviral factorsSemantic proximity Read ↗

MicroRNA and Pathogenesis of Enterovirus InfectionSemantic proximity Read ↗

Exosomal MicroRNA-155 Inhibits Enterovirus A71 Infection by Targeting PICALMSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.