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Article

DNA topoisomerase IIIβ promotes cyst generation by inducing cyst wall protein gene expression in Giardia lamblia.

Open biology - 1 Feb 2020

Sun Chin-Hung, Weng Shih-Che, Wu Jui-Hsuan, Tung Szu-Yu, Su Li-Hsin, Lin Meng-Hsuan, Lee Gilbert Aaron

Abstract excerpt

Giardia lamblia causes waterborne diarrhoea by transmission of infective cysts. Three cyst wall proteins are highly expressed in a concerted manner during encystation of trophozoites into cysts. However, their gene regulatory mechanism is still largely unknown. DNA topoisomerases control topological homeostasis of genomic DNA during replication, transcription and chromosome segregation. They are involved in a...

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Identifiers

PMID: 32019477
DOI: 10.1098/rsob.190228
PMCID: PMC7058931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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