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Regulation of Cyst Wall Protein Promoters by Myb2 in Giardia lamblia

4 Sept 2008

Abstract excerpt

Myb family transcription factors are important in regulating cell proliferation, differentiation, and cell cycle progression. Giardia lamblia differentiates into infectious cysts to survive outside of the host. During encystation, genes encoding cyst wall proteins (CWPs) are coordinately induced. We have identified an encystation-induced Myb2 protein, which binds to the promoter regions of the cwp genes and myb2...

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PMID: 18768462
DOI: 10.1074/jbc.m805023200

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