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Article

Rezafungin In Vitro Activity against Contemporary Nordic Clinical Candida Isolates and Candida auris Determined by the EUCAST Reference Method.

Antimicrobial agents and chemotherapy - 24 Mar 2020

Helleberg Marie, Jørgensen Karin Meinike, Hare Rasmus Krøger, Datcu Raluca, Chowdhary Anuradha, Arendrup Maiken Cavling

Abstract excerpt

Rezafungin (formerly CD101) is a novel echinocandin in clinical development. EUCAST epidemiological cutoff values (ECOFFs) have not yet been established. We determined the in vitro activity of rezafungin and comparators against 1,293 Nordic yeast isolates and 122 Indian Candida auris isolates and established single-center wild-type upper limits (WT-UL). The isolates (19 Candida spp. and 13 other yeast species)...

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Identifiers

PMID: 32015032
DOI: 10.1128/AAC.02438-19
PMCID: PMC7179313

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