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Article

Accelerated viral dynamics in bat cell lines, with implications for zoonotic emergence.

eLife - 3 Feb 2020

Brook Cara E, Boots Mike, Chandran Kartik, Dobson Andrew P, Drosten Christian, Graham Andrea L, Grenfell Bryan T, Müller Marcel A, Ng Melinda, Wang Lin-Fa, van Leeuwen Anieke

Abstract excerpt

Bats host virulent zoonotic viruses without experiencing disease. A mechanistic understanding of the impact of bats' virus hosting capacities, including uniquely constitutive immune pathways, on cellular-scale viral dynamics is needed to elucidate zoonotic emergence. We carried out virus infectivity assays on bat cell lines expressing induced and constitutive immune phenotypes, then developed a theoretical model...

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Identifiers

PMID: 32011232
DOI: 10.7554/eLife.48401
PMCID: PMC7064339

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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