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Article

Modeling Normal and Dysbiotic Subgingival Microbiomes: Effect of Nutrients

30 Jan 2020

Abstract excerpt

Screening for microbiome modulators requires availability of a high-throughput in vitro model that replicates subgingival dysbiosis and normobiosis, with a tool to measure microbial dysbiosis. Here, we tested various formulations to grow health- and periodontitis-associated subgingival microbiomes in parallel, and we describe a new subgingival dysbiosis index. Subgingival plaque samples pooled from 5 healthy...

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PMID: 31999932
DOI: 10.1177/0022034520902452

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