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Article

Telomeres as Therapeutic Targets in Heart Disease

1 Nov 2019

Abstract excerpt

Telomeres are double-stranded repeats of G-rich tandem DNA sequences that gradually shorten with each cell division. Aging, inflammation, and oxidative stress accelerate the process of telomere shortening. Telomerase counteracts this process by maintaining and elongating the telomere length. Patients with atherosclerotic diseases and cardiovascular risk factors (e.g., smoking, obesity, sedentary lifestyle, and...

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Share to Genetics, Aging, and Longevity in Model Organisms
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PMID: 31998853
DOI: 10.1016/j.jacbts.2019.05.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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