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Article

Prognosis, Biology, and Targeting of TP53 Dysregulation in Multiple Myeloma.

Cells - 24 Jan 2020

Flynt Erin, Bisht Kamlesh, Sridharan Vinidhra, Ortiz María, Towfic Fadi, Thakurta Anjan

Abstract excerpt

Multiple myeloma (MM) is the second most common hematological cancer and is characterized by genetic features including translocations, chromosomal copy number aberrations, and mutations in key oncogene and tumor suppressor genes. Dysregulation of the tumor suppressor TP53 is important in the pathogenesis of many cancers, including MM. In newly-diagnosed MM patients, TP53 dysregulation occurs in three subsets:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31991614
DOI: 10.3390/cells9020287
PMCID: PMC7072230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Prognosis, Biology, and Targeting of TP53 Dysregulation in Multiple Myeloma.PMID 31991614Read ↗

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