Article
The molecular patterns of resistance to anti-tuberculosis drugs: an analysis from Istanbul, Turkey.
Journal of chemotherapy (Florence, Italy) - 1 Apr 2020
Yazisiz Hatice, Hircin Cenger Derya, Uçarman Nilay, Altin Sedat
Abstract excerpt
Resistances to anti-tuberculosis (TB) drugs are related to the mutations in the genome of the Mycobacterium tuberculosis complex (MTBC). To expose the genomic mutations that cause anti-TB drug resistance. The GenoType MTBDRplus and MTBDRsl assays were used to detect genetic mutations. In this study of 1329 MTBC isolates, the sensitivities and specificities of genotypic methods for the detection of isoniazid...
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