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ABCA1 Variants rs1800977 (C69T) and rs9282541 (R230C) Are Associated with Susceptibility to Type 2 Diabetes.

Public health genomics - 1 Jan 2020

Du Weiping, Hu Zhixi, Wang Li, Li Miaomiao, Zhao Dong, Li Hui, Wei Junsheng, Zhang Rui

Abstract excerpt

OBJECTIVE: Accumulated evidence suggests that ATP-binding cassette A1 transporter (ABCA1) contributes to secreting insulin in pancreatic β-cells and amyloid beta formation. This study aimed to investigate the association between three single nucleotide polymorphisms (SNPs) of ABCA1 and susceptibility to type 2 diabetes mellitus (T2DM) in a Han Chinese population. METHODS: A total of 996 T2DM patients and 1,002...

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Share to ATP Binding Cassette Transporter 1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 31982877
DOI: 10.1159/000505344

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