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Article

Role of adenosine deaminase 2 gene variants in pediatric deficiency of adenosine deaminase 2: A structural biological approach.

Molecular medicine reports - 1 Feb 2020

Zervou Maria I, Goulielmos George N, Matalliotakis Michail, Matalliotaki Charoula, Spandidos Demetrios A, Eliopoulos Elias

Abstract excerpt

Adenosine deaminase 2 (ADA2) belongs to the novel family of adenosine deaminase growth factors (ADGFs), which play an important role in tissue development. The deficiency of adenosine deaminase 2 (DADA2) is a recently recognized autosomal recessive autoinflammatory disease, characterized by various systemic vascular and inflammatory manifestations, which is associated with ADA2 mutations. Considering that a...

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Identifiers

PMID: 31974608
DOI: 10.3892/mmr.2019.10862
PMCID: PMC6947897

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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