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Article

The TUSC2 Tumour Suppressor Inhibits the Malignant Phenotype of Human Thyroid Cancer Cells via SMAC/DIABLO Protein.

International journal of molecular sciences - 21 Jan 2020

Mariniello Raffaela Mariarosaria, Orlandella Francesca Maria, Stefano Anna Elisa De, Iervolino Paola Lucia Chiara, Smaldone Giovanni, Luciano Neila, Cervone Nara, Munciguerra Francesco, Esposito Silvia, Mirabelli Peppino, Salvatore Giuliana

Abstract excerpt

Thyroid carcinoma is the most common endocrine cancer and includes different forms. Among these, anaplastic thyroid carcinoma (ATC) is the rarest but the most lethal subtype, compared to papillary thyroid carcinoma (PTC) which shows an overall good prognosis. We have previously showed that Tumor Suppressor Candidate 2 (TUSC2), a known tumour suppressor gene, is downregulated in human PTC and ATC compared to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31973107
DOI: 10.3390/ijms21030702
PMCID: PMC7037188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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