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A network pharmacology approach to explore the potential targets underlying the effect of sinomenine on rheumatoid arthritis

20 Jan 2020

Abstract excerpt

OBJECTIVE: To explore the potential targets underlying the effect of sinomenine (SIN) on rheumatoid arthritis (RA) by utilizing a network pharmacology approach. METHODS: SIN and its drug targets were identified using network analysis followed by experimental validation. First, the Pharmmapper, UniProt and GeneCards databases were mined for information relevant to the prediction of SIN targets and RA-related...

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PMID: 31972421
DOI: 10.1016/j.intimp.2020.106201

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