The transcription factor PrtT and its target protease profiles in Aspergillus niger are negatively regulated by carbon sources.

doi:10.1007/s10529-020-02806-3

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Article

The transcription factor PrtT and its target protease profiles in Aspergillus niger are negatively regulated by carbon sources.

Biotechnology letters - 1 Apr 2020

Huang Lianggang, Dong Liangbo, Wang Bin, Pan Li

Abstract excerpt

OBJECTIVE: To survey genome-scale protease profiles regulated by the Aspergillus niger transcription factor PrtT and further controlled by carbon sources. RESULTS: The PrtT disruption mutant (delprtT) and overexpression (OEprtT) strains were successfully generated and further confirmed by phenotypic and protease activity analysis. RNA-seq analysis of WT and mutants identified 32 differentially expressed protease...

Topics

Aspergillus niger
Carbon
Fungal Proteins
Gene Expression Profiling
Gene Expression Regulation, Fungal
Mutation
Peptide Hydrolases
Phenotype
Promoter Regions, Genetic
Sequence Analysis, RNA
Trans-Activators
Transcription Factors

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Identifiers

PMID: 31970554
DOI: 10.1007/s10529-020-02806-3

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