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Article

bHLH121 Functions as a Direct Link that Facilitates the Activation of FIT by bHLH IVc Transcription Factors for Maintaining Fe Homeostasis in Arabidopsis.

Molecular plant - 6 Apr 2020

Lei Rihua, Li Yang, Cai Yuerong, Li Chenyang, Pu Mengna, Lu Chengkai, Yang Yujie, Liang Gang

Abstract excerpt

Iron (Fe) deficiency is prevalent in plants grown in neutral or alkaline soil. Plants have evolved sophisticated mechanisms that regulate Fe homeostasis, ensuring survival. In Arabidopsis, FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR (FIT) is a crucial regulator of Fe-deficiency response. FIT is activated indirectly by basic helix-loop-helix (bHLH) IVc transcription factors (TFs) under Fe deficiency;...

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Identifiers

PMID: 31962167
DOI: 10.1016/j.molp.2020.01.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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bHLH121 Functions as a Direct Link that Facilitates the Activation of FIT by bHLH IVc Transcription Factors for Maintaining Fe Homeostasis in Arabidopsis.PMID 31962167Read ↗

bHLH11 inhibits bHLH IVc proteins by recruiting the TOPLESS/TOPLESS-RELATED corepressors.Semantic proximity Read ↗

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Iron deficiency-mediated stress regulation of four subgroup Ib BHLH genes in Arabidopsis thaliana.Semantic proximity Read ↗

Interaction between the bHLH transcription factor FIT and ETHYLENE INSENSITIVE3/ETHYLENE INSENSITIVE3-LIKE1 reveals molecular linkage between the regulation of iron acquisition and ethylene signaling in Arabidopsis.Semantic proximity Read ↗

Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana.Semantic proximity Read ↗

FIT, the FER-LIKE IRON DEFICIENCY INDUCED TRANSCRIPTION FACTOR in Arabidopsis.Semantic proximity Read ↗

The essential basic helix-loop-helix protein FIT1 is required for the iron deficiency response.Semantic proximity Read ↗

The 14-3-3 protein GENERAL REGULATORY FACTOR11 (GRF11) acts downstream of nitric oxide to regulate iron acquisition in Arabidopsis thaliana.Semantic proximity Read ↗

ZINC FINGER OF ARABIDOPSIS THALIANA12 (ZAT12) Interacts with FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR (FIT) Linking Iron Deficiency and Oxidative Stress Responses.Semantic proximity Read ↗

The transcription factor WRKY13 activates BRUTUS to maintain iron homeostasis in Arabidopsis.Semantic proximity Read ↗

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