Article
Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritisation.
The pharmacogenomics journal - 1 Oct 2020
King Charlotte, McKenna Amanda, Farzan Niloufar, Vijverberg Susanne J, van der Schee Marc P, Maitland-van der Zee Anke H, Arianto Lambang, Bisgaard Hans, BØnnelykke Klaus, Berce Vojko, PotoČnik Uros, Repnik Katja, Carleton Bruce, Daley Denise, Chew Fook Tim, Chiang Wen Chin, Sio Yang Yie, Cloutier Michelle M, Den Dekker Herman T, Duijts Liesbeth, de Jongste Johan C, Dijk F Nicole, Flores Carlos, Hernandez-Pacheco Natalia, Mukhopadhyay Somnath, Basu Kaninika, Tantisira Kelan G, Verhamme Katia M, Celedón Juan C, Forno Erick, Canino Glorisa, Francis Ben, Pirmohamed Munir, Sinha Ian, Hawcutt Daniel B
Abstract excerpt
A systematic review of pharmacogenomic studies capturing adverse drug reactions (ADRs) related to asthma medications was undertaken, and a survey of Pharmacogenomics in Childhood Asthma (PiCA) consortia members was conducted. Studies were eligible if genetic polymorphisms were compared with suspected ADR(s) in a patient with asthma, as either a primary or secondary outcome. Five studies met the inclusion...
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