Article
Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia.
Genome medicine - 16 Jan 2020
Wyres Kelly L, Nguyen To N T, Lam Margaret M C, Judd Louise M, van Vinh Chau Nguyen, Dance David A B, Ip Margaret, Karkey Abhilasha, Ling Clare L, Miliya Thyl, Newton Paul N, Lan Nguyen Phu Huong, Sengduangphachanh Amphone, Turner Paul, Veeraraghavan Balaji, Vinh Phat Voong, Vongsouvath Manivanh, Thomson Nicholas R, Baker Stephen, Holt Kathryn E
Abstract excerpt
BACKGROUND: Klebsiella pneumoniae is a leading cause of bloodstream infection (BSI). Strains producing extended-spectrum beta-lactamases (ESBLs) or carbapenemases are considered global priority pathogens for which new treatment and prevention strategies are urgently required, due to severely limited therapeutic options. South and Southeast Asia are major hubs for antimicrobial-resistant (AMR) K. pneumoniae and...
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