Article
Absence of dynamic hyperinflation during exhaustive exercise in severe COPD reflects submaximal IC maneuvers rather than a nonhyperinflator phenotype.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Mar 2020
Luo Yuan-Ming, Qiu Zhi-Hui, Wang Yuan, He Bai-Ting, Qin Hua, Xiao Si-Chang, Luo Ying-Mei, Steier Joerg, Moxham John, Polkey Michael I
Abstract excerpt
Approximately 20% of chronic obstructive pulmonary disease (COPD) patients have been considered to have a "nonhyperinflator phenotype." However, this judgment depends on patients making a fully maximal inspiratory capacity (IC) maneuver at rest, since the IC during exercise is compared with this baseline measurement. We hypothesized that IC maneuvers at rest are sometimes submaximal and tested this hypothesis by...
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