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Article

Autophagy related gene expression status in patients diagnosed with azoospermia: A cross-sectional study.

The journal of gene medicine - 1 Apr 2020

Asgari Rezvan, Bakhtiari Mitra, Rezazadeh Davood, Vaisi-Raygani Asad, Mansouri Kamran

Abstract excerpt

BACKGROUND: Autophagy affects various aspects of the male reproductive system. Any defects in this process may lead to azoospermia. However, the exact molecular mechanisms of the autophagy pathway have remained largely obscure. Therefore, the present study aimed to investigate levels of autophagy pathway gene expression (i.e. Lc3B, Beclin1, ATG5 and Bcl2) in azoospermic patients. METHODS: The levels of Lc3B,...

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PMID: 31944482
DOI: 10.1002/jgm.3161

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