Article
Fibroblasts in urothelial bladder cancer define stroma phenotypes that are associated with clinical outcome.
Scientific reports - 14 Jan 2020
Mezheyeuski Artur, Segersten Ulrika, Leiss Lina Wik, Malmström Per-Uno, Hatina Jiri, Östman Arne, Strell Carina
Abstract excerpt
Little attention was given to the interaction between tumor and stromal cells in urothelial bladder carcinoma (UBC). While recent studies point towards the existence of different fibroblast subsets, no comprehensive analyses linking different fibroblast markers to UBC patient survival have been performed so far. Through immunohistochemical analysis of five selected fibroblast markers, namely alpha smooth muscle...
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