Article
Histologic Classification and Molecular Signature of Polymorphous Adenocarcinoma (PAC) and Cribriform Adenocarcinoma of Salivary Gland (CASG): An International Interobserver Study.
The American journal of surgical pathology - 1 Apr 2020
Xu Bin, Barbieri Andrea L, Bishop Justin A, Chiosea Simon I, Dogan Snjezana, Di Palma Silvana, Faquin William C, Ghossein Ronald, Hyrcza Martin, Jo Vickie Y, Lewis James S, Lozada John R, Michal Michal, Pareja Fresia G, Perez-Ordonez Bayardo, Prasad Manju L, Purgina Bibianna, Reis-Filho Jorge S, Scognamiglio Theresa, Sebastiao Ana P M, Seethala Raja R, Skálová Alena, Smith Stephen M, Tekkeşin Merva S, Thompson Lester D R, Wasseman Jason K, Wenig Bruce M, Weinreb Ilan, Katabi Nora
Abstract excerpt
Polymorphous adenocarcinoma (PAC) shows histologic diversity with streaming and targetoid features whereas cribriform adenocarcinoma of salivary gland (CASG) demonstrates predominantly cribriform and solid patterns with glomeruloid structures and optically clear nuclei. Opinions diverge on whether CASG represents a separate entity or a variant of PAC. We aimed to assess the level of agreement among 25 expert Head...
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