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Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer

8 Jan 2020

Abstract excerpt

Abstract The spatial organization of different types of cells in tumor tissues reveals important information about the tumor microenvironment (TME). To facilitate the study of cellular spatial organization and interactions, we developed Histology-based Digital-Staining, a deep learning-based computation model, to segment the nuclei of tumor, stroma, lymphocyte, macrophage, karyorrhexis, and red blood cells from...

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PMID: 31915129
DOI: 10.1158/0008-5472.can-19-1629

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