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Article

Chromatin remodeling dysfunction extends the etiological spectrum of schizophrenia: a case report.

BMC medical genetics - 8 Jan 2020

Poisson Alice, Chatron Nicolas, Labalme Audrey, Fourneret Pierre, Ville Dorothée, Mathieu Marie Laure, Sanlaville Damien, Demily Caroline, Lesca Gaëtan

Abstract excerpt

BACKGROUND: The role of deleterious copy number variations in schizophrenia is well established while data regarding pathogenic variations remain scarce. We report for the first time a case of schizophrenia in a child with a pathogenic mutation of the chromodomain helicase DNA binding protein 2 (CHD2) gene. CASE PRESENTATION: The proband was the second child of unrelated parents. Anxiety and sleep disorders...

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Identifiers

PMID: 31914951
DOI: 10.1186/s12881-019-0946-0
PMCID: PMC6950831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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