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Article

Molecular detection of H. pylori antibiotic-resistant genes and molecular docking analysis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jan 2020

Chu Aining, Wang Dan, Guo Qianqian, Lv Zhi, Yuan Yuan, Gong Yuehua

Abstract excerpt

To explore the mutation characteristics of H. pylori resistance-related genes to antibiotics of clarithromycin (CAM), levofloxacin (LVX) and metronidazole, 23SrRNA, gyrA, gyrB, rdxA, and frxA genes were amplified and sequenced, respectively. Molecular docking study was performed to explore molecular interactions between chemotherapeutic agents and target proteins. In the CAM-resistant strains, the mutation rate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31914672
DOI: 10.1096/fj.201900774R

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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