Article
Craniofacial second primary tumors in patients with germline retinoblastoma previously treated with external beam radiotherapy: A retrospective institutional analysis.
Pediatric blood & cancer - 1 Apr 2020
Jiménez Irene, Laé Marick, Tanguy Marie-Laure, Savignoni Alexia, Gauthier-Villars Marion, Desjardins Laurence, Cassoux Nathalie, Dendale Rémi, Rodriguez Joseph, Doz François, Brisse Hervé J, Aerts Isabelle
Abstract excerpt
BACKGROUND: The long-term survival of germline retinoblastoma patients is decreased due to the risk of second primary tumors (SPTs) that occur years after the diagnosis of retinoblastoma. This risk is related to genetic predisposition and other factors, such as the treatment of retinoblastoma by external beam radiotherapy (EBRT). PROCEDURE: We studied the incidence, risk factors, and prognosis of specific...
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