Article
Second primary osteosarcomas in patients with retinoblastoma.
Japanese journal of clinical oncology - 1 Dec 2015
Fujiwara Tomohiro, Fujiwara Miyuki, Numoto Kunihiko, Ogura Koichi, Yoshida Akihiko, Yonemoto Tsukasa, Suzuki Shigenobu, Kawai Akira
Abstract excerpt
OBJECTIVE: Second primary malignancies have become the leading cause of death in retinoblastoma survivors. Although osteosarcoma is the most common second malignancy, little is known about its clinical and therapeutic features. METHODS: We retrospectively reviewed a database of patients with retinoblastoma and osteosarcoma occurring as a second malignancy between 1964 and 2010 at the National Cancer Center...
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