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Article

Cerebrospinal fluid MinION sequencing of 16S rRNA gene for rapid and accurate diagnosis of bacterial meningitis

28 Dec 2019

Abstract excerpt

We read with interest recent articles in this journal regarding the utility of next-generation sequencing for the diagnosis bacterial meningitis.1,2 Bacterial meningitis causes substantial morbidity and mortality worldwide.3 Rapid identification of the microorganisms is essential for early initiation of appropriate antimicrobial therapy, thereby improving clinical outcome. Yet routine diagnostic methods fail to...

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PMID: 31891725
DOI: 10.1016/j.jinf.2019.12.011

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