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Virus-based SELEX (viro-SELEX) allows development of aptamers targeting knotty proteins

23 Dec 2019

Abstract excerpt

It has been 100 years since the worst flu (Spanish flu) mankind has ever experienced. Rapid, accurate diagnosis and subtyping of flu are still an urgent unmet medical need. By using surrogate virus-based SELEX (viro-SELEX), we report here multiple advances incorporated into the field of flu diagnostics: (i) aptamers that can bind to the native virus well even though they cannot bind strongly to a recombinant...

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PMID: 31868873
DOI: 10.1039/c9an01943j

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