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Article

Acromegaly in the setting of Tatton-Brown-Rahman Syndrome.

Pituitary - 1 Apr 2020

Hage C, Sabini E, Alsharhan H, Fahrner J A, Beckers A, Daly A, Salvatori R

Abstract excerpt

PURPOSE: Tatton-Brown-Rahman syndrome (TBRS) is a newly defined genetic entity characterized by overgrowth and intellectual disability, resulting from germline mutations in the gene encoding DNA methyltransferase 3 alpha (DNMT3A). Affected individuals with benign and malignant tumors have been reported; to our knowledge pituitary adenomas (and other tumors identified in our patient) have not yet been described in...

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Source

Identifiers

PMID: 31858400
DOI: 10.1007/s11102-019-01019-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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