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Article

A muscular hypotonia-associated STIM1 mutant at R429 induces abnormalities in intracellular Ca2+ movement and extracellular Ca2+ entry in skeletal muscle.

Scientific reports - 16 Dec 2019

Choi Jun Hee, Huang Mei, Hyun Changdo, Oh Mi Ri, Lee Keon Jin, Cho Chung-Hyun, Lee Eun Hui

Abstract excerpt

Stromal interaction molecule 1 (STIM1) mediates extracellular Ca2+ entry into the cytosol through a store-operated Ca2+ entry (SOCE) mechanism, which is involved in the physiological functions of various tissues, including skeletal muscle. STIM1 is also associated with skeletal muscle diseases, but its pathological mechanisms have not been well addressed. The present study focused on examining the pathological...

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Identifiers

PMID: 31844136
DOI: 10.1038/s41598-019-55745-z
PMCID: PMC6915709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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