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Implications of gut microbiota dysbiosis and metabolic changes in prion disease

16 Dec 2019

Abstract excerpt

Evidence of the gut microbiota influencing neurodegenerative diseases has been reported for several neural diseases. However, there is little insight regarding the relationship between the gut microbiota and prion disease. Here, using fecal samples of 12 prion-infected mice and 25 healthy controls, we analyzed the structure of the gut microbiota and metabolic changes by 16S rRNA sequencing and LC-MS-based...

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PMID: 31837420
DOI: 10.1016/j.nbd.2019.104704

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