Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hereditary Leiomyomatosis and Renal Cell Cancer: Clinical, Molecular, and Screening Features in a Cohort of 185 Affected Individuals.

European urology oncology - 1 Dec 2020

Forde Claire, Lim Derek H K, Alwan Yousef, Burghel George, Butland Laura, Cleaver Ruth, Dixit Abhijit, Evans D Gareth, Hanson Helen, Lalloo Fiona, Oliveira Pedro, Vialard Lindsey, Wallis Yvonne, Maher Eamonn R, Woodward Emma R

Abstract excerpt

BACKGROUND: Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a tumour predisposition syndrome characterised by predisposition to cutaneous and uterine leiomyomata and renal cell carcinoma (RCC). OBJECTIVE: To define the clinical findings, molecular genetics, and prognosis in a cohort of 69 families with a fumarate hydratase (FH) pathogenic variant and/or clinical features of HLRCC. DESIGN, SETTING, AND...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Renal Cell
Share to Early Detection of Cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fumarate Hydratase

Share to Kidney Neoplasms

Share to Leiomyomatosis

Share to Medical History Taking

Share to Neoplastic Syndromes, Hereditary

Share to Uterine Neoplasms

Source

Identifiers

PMID: 31831373
DOI: 10.1016/j.euo.2019.11.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hereditary Leiomyomatosis and Renal Cell Cancer: Clinical, Molecular, and Screening Features in a Cohort of 185 Affected Individuals.PMID 31831373Read ↗

Novel mutations in FH and expansion of the spectrum of phenotypes expressed in families with hereditary leiomyomatosis and renal cell cancer.Semantic proximity Read ↗

Reassessing the clinical spectrum associated with hereditary leiomyomatosis and renal cell carcinoma syndrome in French FH mutation carriers.Semantic proximity Read ↗

Novel morphological and genetic features of fumarate hydratase deficient renal cell carcinoma in HLRCC syndrome patients with a tailored therapeutic approachSemantic proximity Read ↗

Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome in Spain: Clinical and Genetic CharacterizationSemantic proximity Read ↗

Hereditary leiomyomatosis and renal cell cancer in families referred for fumarate hydratase germline mutation analysis.Semantic proximity Read ↗

Estimation of the carrier frequency of fumarate hydratase alterations and implications for kidney cancer risk in hereditary leiomyomatosis and renal cancer.Semantic proximity Read ↗

Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC): Report of a Family Pedigree.Semantic proximity Read ↗

Renal cell carcinoma in young FH mutation carriers: case series and review of the literatureSemantic proximity Read ↗

Hereditary leiomyomatosis and renal cell carcinomaSemantic proximity Read ↗

Hereditary Leiomyomatosis and Renal Cell Cancer.Semantic proximity Read ↗

Fumarate Hydratase-deficient Uterine Leiomyomas Occur in Both the Syndromic and Sporadic Settings.Semantic proximity Read ↗

Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) SyndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.