Dissecting the Role of NF-κb Protein Family and Its Regulators in Rheumatoid Arthritis Using Weighted Gene Co-Expression Network

Abstract excerpt

Rheumatoid arthritis (RA) is a chronic synovial auto-inflammatory disease that destructs the cartilage and bone, leading to disability. The functional regulation of major immunity related pathways like NF-kB which is involved in the chronic inflammatory reactions underlying the development of RA remains to be explored. Therefore, this study has adopted statistical and knowledge based systemic investigations (like...

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