Article
Genetic Paths to Evolutionary Rescue and the Distribution of Fitness Effects Along Them.
Genetics - 1 Feb 2020
Osmond Matthew M, Otto Sarah P, Martin Guillaume
Abstract excerpt
The past century has seen substantial theoretical and empirical progress on the genetic basis of adaptation. Over this same period, a pressing need to prevent the evolution of drug resistance has uncovered much about the potential genetic basis of persistence in declining populations. However, we have little theory to predict and generalize how persistence-by sufficiently rapid adaptation-might be realized in...
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