Article
Multiscale analysis for patterns of Zika virus genotype emergence, spread, and consequence.
PloS one - 1 Jan 2019
Borucki Monica K, Collette Nicole M, Coffey Lark L, Van Rompay Koen K A, Hwang Mona H, Thissen James B, Allen Jonathan E, Zemla Adam T
Abstract excerpt
The question of how Zika virus (ZIKV) changed from a seemingly mild virus to a human pathogen capable of microcephaly and sexual transmission remains unanswered. The unexpected emergence of ZIKV's pathogenicity and capacity for sexual transmission may be due to genetic changes, and future changes in phenotype may continue to occur as the virus expands its geographic range. Alternatively, the sheer size of the...
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