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Article

TIMP1 Is A Potential Key Gene Associated With The Pathogenesis And Prognosis Of Ulcerative Colitis-Associated Colorectal Cancer

1 Oct 2019

Abstract excerpt

Purpose: Colorectal cancer (CRC) is the third most frequently diagnosed cancer worldwide. As a high-risk factor for CRC, ulcerative colitis (UC) has been demonstrated to lead to epithelial dysplasia, DNA damage, and eventually cancer. There are approximately 18% of patients with UC may develop CRC. Patients and methods: The gene expression profiles were retrieved from the Gene Expression Omnibus. The Database for...

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PMID: 31802901
DOI: 10.2147/ott.s222608

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