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Article

ACE-Triggered Hypertension Incites Stroke: Genetic, Molecular, and Therapeutic Aspects.

Neuromolecular medicine - 1 Jun 2020

Vasudeva Kanika, Balyan Renuka, Munshi Anjana

Abstract excerpt

Stroke is the second largest cause of death worldwide. Angiotensin converting enzyme (ACE) gene has emerged as an important player in the pathogenesis of hypertension and consequently stroke. It encodes ACE enzyme that converts the inactive decapeptide angiotensin I to active octapeptide, angiotensin II (Ang II). Dysregulation in the expression of ACE gene, on account of genetic variants or regulation by miRNAs,...

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Identifiers

PMID: 31802381
DOI: 10.1007/s12017-019-08583-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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