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Article

Predictive impact of rare genomic copy number variations in siblings of individuals with autism spectrum disorders.

Nature communications - 5 Dec 2019

D'Abate L, Walker S, Yuen R K C, Tammimies K, Buchanan J A, Davies R W, Thiruvahindrapuram B, Wei J, Brian J, Bryson S E, Dobkins K, Howe J, Landa R, Leef J, Messinger D, Ozonoff S, Smith I M, Stone W L, Warren Z E, Young G, Zwaigenbaum L, Scherer S W

Abstract excerpt

Identification of genetic biomarkers associated with autism spectrum disorders (ASDs) could improve recurrence prediction for families with a child with ASD. Here, we describe clinical microarray findings for 253 longitudinally phenotyped ASD families from the Baby Siblings Research Consortium (BSRC), encompassing 288 infant siblings. By age 3, 103 siblings (35.8%) were diagnosed with ASD and 54 (18.8%) were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 31801954
DOI: 10.1038/s41467-019-13380-2
PMCID: PMC6892938

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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