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Article

A truncated form of a transcription factor Mamo activates vasa in Drosophila embryos.

Communications biology - 1 Jan 2019

Nakamura Shoichi, Hira Seiji, Fujiwara Masato, Miyagata Nasa, Tsuji Takuma, Kondo Akane, Kimura Hiroshi, Shinozuka Yuko, Hayashi Makoto, Kobayashi Satoru, Mukai Masanori

Abstract excerpt

Expression of the vasa gene is associated with germline establishment. Therefore, identification of vasa activator(s) should provide insights into germline development. However, the genes sufficient for vasa activation remain unknown. Previously, we showed that the BTB/POZ-Zn-finger protein Mamo is necessary for vasa expression in Drosophila. Here, we show that the truncated Mamo lacking the BTB/POZ domain...

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Identifiers

PMID: 31799425
DOI: 10.1038/s42003-019-0663-4
PMCID: PMC6868150

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