Article
Heterozygote carriers of mutations in the F11 gene, encoding Factor XI, have normal coagulation by thromboelastography during pregnancy.
International journal of obstetric anesthesia - 1 May 2020
Ciampa E J, Liu N, Stiles J, Carani J L, Li Y, Hess P E
Abstract excerpt
BACKGROUND: Evidence to guide clinical decision-making in pregnant women who are usually asymptomatic, but identified as heterozygote carriers of F11 mutations, is lacking. We hypothesized that women identified on prenatal screening as heterozygous for a mutation in the F11 allele would have minimal evidence of an in vitro coagulation abnormality. METHODS: We prospectively enrolled women identified by prenatal...
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