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Article

A novel missense mutation in the factor XII gene in a litter of cats with factor XII deficiency.

The Journal of veterinary medical science - 3 May 2017

Maruyama Haruhiko, Hosoe Haruki, Nagamatsu Kota, Kano Rui, Kamata Hiroshi

Abstract excerpt

The feline F12 gene was examined to identify a mutation associated with coagulation factor XII (FXII) deficiency in a litter of 6 cats, including 2 cats with severely reduced FXII activity (7.1 and 9.3%, respectively) and 4 cats with moderately reduced FXII activity (range 36.0 to 46.3%). Cats with severely reduced FXII activity were homozygous for a G to C missense mutation in exon 13 of the F12 gene, resulting...

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Identifiers

PMID: 28392508
DOI: 10.1292/jvms.16-0602
PMCID: PMC5447966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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