Next generation sequencing of human enterovirus strains from an outbreak of enterovirus A71 shows applicability to outbreak investigations.

doi:10.1016/j.jcv.2019.104216

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Article

Next generation sequencing of human enterovirus strains from an outbreak of enterovirus A71 shows applicability to outbreak investigations.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jan 2020

Stelzer-Braid Sacha, Wynn Matthew, Chatoor Richard, Scotch Matthew, Ramachandran Vidiya, Teoh Hooi-Ling, Farrar Michelle A, Sampaio Hugo, Andrews Peter Ian, Craig Maria E, MacIntyre C Raina, Varadhan Hemalatha, Kesson Alison, Britton Philip N, Newcombe James, Rawlinson William D

Abstract excerpt

BACKGROUND: The most recent documented Australian outbreak of enterovirus A71 (EV-A71) occurred in Sydney from 2012 to 2013. Over a four-month period more than 100 children presented to four paediatric hospitals with encephalitic presentations including fever and myoclonic jerks. The heterogeneous presentations included typical encephalomyelitis, and cardiopulmonary complications. OBJECTIVES: To characterise the...

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PMID: 31790967
DOI: 10.1016/j.jcv.2019.104216
PMCID: PMC7384352

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