Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical importance of long non‑coding RNA LINC00460 expression in EGFR‑mutant lung adenocarcinoma.

International journal of oncology - 1 Jan 2020

Nakano Yuta, Isobe Kazutoshi, Kobayashi Hiroshi, Kaburaki Kyohei, Isshiki Takuma, Sakamoto Susumu, Takai Yujiro, Tochigi Naobumi, Mikami Tetsuo, Iyoda Akira, Homma Sakae, Kishi Kazuma

Abstract excerpt

Long non‑coding RNAs (lncRNAs) have been reported to be involved in the physiological and pathological processes of tumor pathogenesis, including epithelial‑mesenchymal transition (EMT). However, epidermal growth factor receptor (EGFR)‑tyrosine kinase inhibitor (TKI) resistance is a major challenge in the treatment of advanced and recurrent EGFR‑mutant lung adenocarcinoma. An increased understanding of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma of Lung
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to ErbB Receptors

Share to Protein Kinase Inhibitors

Share to RNA, Long Noncoding

Share to Survival Rate

Share to Tumor Cells, Cultured

Source

Open in PubMed Open full text

Identifiers

PMID: 31789388
DOI: 10.3892/ijo.2019.4919
PMCID: PMC6910175

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical importance of long non‑coding RNA LINC00460 expression in EGFR‑mutant lung adenocarcinoma.PMID 31789388Read ↗

Long non-coding RNA BC087858 induces non-T790M mutation acquired resistance to EGFR-TKIs by activating PI3K/AKT and MEK/ERK pathways and EMT in non-small-cell lung cancer.Semantic proximity Read ↗

C-MYC inducible onco-lncRNA LINC00036 acting as EGFR mRNA stabilizer via RNA-protein and RNA-RNA interactions decreases the sensitivity of gefitinib in human cancerSemantic proximity Read ↗

Long Noncoding RNA LINC00460 Facilitates the Proliferation and Metastasis of Renal Cell Carcinoma via PI3K/AKT Signaling PathwaySemantic proximity Read ↗

Long Non-Coding RNA LINC01559 Exerts Oncogenic Role Via Enhancing Autophagy in Lung AdenocarcinomaSemantic proximity Read ↗

Long non-coding RNA LINC01559 exerts oncogenic role via enhancing autophagy in lung adenocarcinomaSemantic proximity Read ↗

Non-coding RNA LINC00857 is predictive of poor patient survival and promotes tumor progression via cell cycle regulation in lung cancerSemantic proximity Read ↗

Long non-coding RNA linc00673 regulated non-small cell lung cancer proliferation, migration, invasion and epithelial mesenchymal transition by sponging miR-150-5pSemantic proximity Read ↗

Expression profiles of long noncoding RNAs in lung adenocarcinomaSemantic proximity Read ↗

Microarray expression profile of long non-coding RNAs in EGFR-TKIs resistance of human non-small cell lung cancerSemantic proximity Read ↗

Long non-coding RNA LSAMP-1 is down-regulated in non-small cell lung cancer and predicts a poor prognosisSemantic proximity Read ↗

LINC00460-miR-149-5p/miR-150-5p-Mutant p53 Feedback Loop Promotes Oxaliplatin Resistance in Colorectal CancerSemantic proximity Read ↗

LINC00460 modulates KDM2A to promote cell proliferation and migration by targeting miR-342-3p in gastric cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.