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Article

Soluble immune checkpoint-related proteins as predictors of tumor recurrence, survival, and T cell phenotypes in clear cell renal cell carcinoma patients.

Journal for immunotherapy of cancer - 29 Nov 2019

Wang Qinchuan, Zhang Jinhua, Tu Huakang, Liang Dong, Chang David W, Ye Yuanqing, Wu Xifeng

Abstract excerpt

BACKGROUND: Immune checkpoint inhibitors have achieved unprecedented success in cancer immunotherapy. With the exception of a few candidate biomarkers, the prognostic role of soluble immune checkpoint-related proteins in clear cell renal cell cancer (ccRCC) patients is largely uninvestigated. METHODS: We profiled the circulating levels of 14 immune checkpoint-related proteins panel (BTLA, GITR, HVEM, IDO, LAG-3,...

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Topics

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Share to Carcinoma, Renal Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31783776
DOI: 10.1186/s40425-019-0810-y
PMCID: PMC6884764

Genes

BTLA
CD27
CD28
CD80

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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