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Article

Combined genetic mutations and DNA-methylated genes as biomarkers for endometrial cancer detection from cervical scrapings.

Clinical epigenetics - 28 Nov 2019

Liew Phui-Ly, Huang Rui-Lan, Wu Tzu-I, Liao Chi-Chun, Chen Chien-Wen, Su Po-Hsuan, Wang Hui-Chen, Weng Yu-Chun, Lai Hung-Cheng

Abstract excerpt

BACKGROUND: Endometrial cancer is a common gynecologic cancer. Noninvasive molecular biomarkers for triage of high-risk patients for invasive procedures are needed. Based on the success of cytological Pap smear screening, cervical scrapings are a good source of DNA for molecular testing. In addition to genetic lesions, DNA methylation is a promising biomarker. We assessed the usefulness of combining genetic and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31779688
DOI: 10.1186/s13148-019-0765-3
PMCID: PMC6883641

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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