Article
Fragile (X) expression, age and the degree of intellectual handicap in the male.
American journal of medical genetics - 1 Jan 2000
Turner G, Partington M W
Abstract excerpt
The proportion of cells expressing the fra(X) was compared to the guardian's opinion of who was the "brighter" in 31 sibships of 2 or more affected males. Six fra(X) positive males in the normal workforce were compared in a similar way to other affected relatives. A correlation was found between lower values of expression and "brightness" by the Wilcoxson signed rank test (less than 0.01, 2-tail). A decline in...
Topics
- Adult
- Age Factors
- Aged
- Fragile X Syndrome
- Humans
- Intelligence
- Male
- Middle Aged
- Phenotype
- Sex Chromosome Aberrations