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Article

Performance of the Xpert HBV Viral Load assay versus the Aptima Quant assay for quantifying hepatitis B virus DNA.

Diagnostic microbiology and infectious disease - 1 Feb 2020

Abravanel Florence, Lhomme Sébastien, Trémeaux Pauline, Migueres Marion, Harter Agnès, Haslé Catherine, Bruel Patrick, Alric Laurent, Métivier Sophie, Raymond Stéphanie, Izopet Jacques

Abstract excerpt

Quantification of HBV DNA is used for initiating and monitoring antiviral treatment. We have evaluated the Xpert HBV Viral Load (VL) assay on the GeneXpert instrument. We estimated its limit of detection to be 7.5 IU/mL. Reproducibility was 1.1-12.7% as assessed by the coefficients of variation for 3 different samples. The assay was linear from 2 to 8 log10 IU/mL for HBV genotypes A to F. Its clinical performance...

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Identifiers

PMID: 31771903
DOI: 10.1016/j.diagmicrobio.2019.114946

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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