Article
Family History is Associated with Phenotype in Dementia with Lewy Bodies.
Journal of Alzheimer's disease : JAD - 1 Jan 2020
Vergouw Leonie J M, Bosman Brechje, van de Beek Marleen, Salomé Mariet, Hoogers Susanne E, van Steenoven Inger, Roks Gerwin, Bonifati Vincenzo, van Swieten John C, Lemstra Afina W, de Jong Frank Jan
Abstract excerpt
It is currently unknown whether patients with dementia with Lewy bodies (DLB) with relatives with dementia or Parkinson's disease (familial DLB patients) have a different phenotype than sporadic DLB patients. In this study, we aimed to examine disease onset, rate of cognitive decline, survival, and Alzheimer's disease (AD) biomarkers in patients with familial DLB (n = 154) and sporadic DLB (n = 137), using linear...
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