Article
[RAS mutations at the molecular tumor conference].
Der Pathologe - 1 Dec 2019
Schäfer R
Abstract excerpt
Members of the rat sarcoma (RAS) gene family belong to the most frequently mutated genes that drive pathogenesis and therapy response. As the discovery of their malignant potential dates back more than three decades, cellular mutated RAS genes and their products belong to the best characterized cancer genes. Despite urgent clinical needs, RAS therapies are still elusive and limited to preclinical studies....
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